Investors have been weighing the odds of further escalation in the conflict and spillover into the broader oil-rich Middle East.

Although Iran maintains that its nuclear program is for peaceful energy purposes, Israel has long seen it as a threat. Israeli strikes have hit three of Iran’s nuclear facilities — Natanz, Isfahan and Fordow. Little damage appears visible in satellite imagery of Fordow.

Hundreds of civilians, mostly in Iran, have been killed by dueling airstrikes despite international pleas for de-escalation.

Israel’s military said it hit command centers of Iran’s Revolutionary Guard, while Iranian strikes overnight killed several people.

The Israel Defense Forces said the air force had launched strikes against missile sites in central Iran, as the Middle East conflict entered a fourth day.

The warning came on the fourth day of the conflict, when the Israeli military claimed it had achieved air superiority over the Iranian capital and could fly over the city without facing major threats.

Countries trade strikes as tensions grow over larger Middle East conflict - Iranian missiles struck an apartment building in the Galilee region, killing four people, as the countries exchanged fire

The Trump administration on Thursday continued to brace for significant escalation in the Middle East, as President Donald Trump sent mixed signals on how he would view an Israeli strike on Iran's nuclear facilities as the U.