IRRADIATION of bacteria with X-rays causes extensive degradation of DNA 1,2. Chloramphenicol given to bacteria after a dose of 16 kr. enhances considerably the degradation of DNA. At 1 kr., however, ...

A group of scientists from Japan--led by Prof Takashi Kamakura of Tokyo University of Science--has demonstrated, for the first time, the molecular and cellular basis of the "adverse" effects of the ...

THE antibiotic chloramphenicol has been found to inhibit accumulation of salt by slices of red beet tissue and carrot tissue without significantly affecting respiration 1. This supports the hypothesis ...

The first reports on the antimicrobial action of chloramphenicol (Chloromycetin) appeared in the latter part of 1947. 1, 2 During the following year a number of publications described in detail its ...

Although chloramphenicol continues to be the leading single cause of drug-induced aplastic anemia, little progress has been made in elucidating the mechanism of its toxic effect. The reversible ...