During eukaryotic gene expression, different classes of RNA molecules are synthesized in the nucleus and are exported to the cytoplasm by mobile export receptors. Export of tRNA requires a specific ...

In a study that may guide drug design, researchers find organelles encounter varying levels of resistance, depending on their size and speed, as they move through a cell's cytoplasm. Under a ...

One of the most striking features of eukaryotic cells is their capacity to change shape in response to environmental or intrinsic cues driven primarily by their actomyosin cytoskeleton. During gross ...

Just as life pulsates in big vibrant cities, it also prospers in crowded environments inside cells. The interior of cells is densely packed with biomolecules like proteins and nucleic acids. How is ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Small protein molecules almost do not experience the cytoplasm viscosity while moving within the cell. Scientists have now shown that the effect can be described universally to include ...

Forty years ago, a postdoctoral researcher named James McGrath who would go on to spend more than three decades as a clinical geneticist and research scientist at Yale, made a discovery that advanced ...

UC Davis researchers tracked the movement of fluorescent particles inside the cells of microscopic worms, providing novel insights into cellular crowding in a multicellular animal. They found that the ...

The inside of a cell is packed with stuff; from big organelles to small molecules, the cytoplasm is the suspension which contains all those components. Researchers at MIT wanted to know more about how ...

Innovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals.

Multicellularity is one of the most profound phenomena in biology, and relies on the ability of a single cell to reorganize itself into a complex organism. It underpins the diversity in the animal ...