DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

A team of researchers led by HHMI Investigator Michael Rosen has captured the most detailed images yet of the molecules in synthetic chromatin condensates — droplet-like structures of compacted DNA.

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

As tough as medieval chainmail armor and as soft as a contact lens. This material is not taken from science fiction, it is a natural structure made of thousands of DNA circles interlinked with each ...

James Watson, who co-won the Nobel Prize for discovering DNA's structure, was a towering and controversial figure in science. When you purchase through links on our site, we may earn an affiliate ...