The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...

Tampa (BLOOM) – Understanding the intricate process of aging has been a subject of fascination for scientists and researchers. While aging is a natural part of life, recent studies have shed light on ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

Genetics tools have advanced significantly in recent decades, and have allowed scientist to sequence all of the genetic ...

In May 1952, Rosalind Franklin and Raymond Gosling captured Photo 51, a crucial X-ray diffraction image revealing DNA's ...

A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study reveals a ...