A telltale sign of viral invasion, double-stranded RNA sounds cellular alarm bells that touch off a firestorm of interferon. According to a paper published July 7 in Science Translational Medicine, ...

The scientist who discovered hybridization and the "other" double helix describes what it meant to biology. By Alexander Rich Fifty-two years ago I was venturing to the basement of Cal Tech chemistry ...

Scientists have designed a new method for detecting and analyzing double-stranded RNA during the manufacture of messenger RNA products. The team of Anubhav Tripathi, PhD, from Brown University, claim ...

Research reveals key differences between single- and double-stranded RNA, insights that may prove useful to fields from agriculture to medicine. Messenger RNA, or mRNA, has been in the news recently ...

In vitro studies showed that breast cancer cell lines can express TLR3, and that dsRNA can induce up to 80% apoptosis in TLR3+ tumor cell lines within 48h of culture. This pro-apoptotic effect of ...

How does aggregated tau wreak damage? In the January 6 Science Advances, researchers led by Bess Frost at the University of Texas Health San Antonio make a case for tau unleashing double-stranded RNA.

There are many different ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called ...

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for myotonic dystrophy type 1 (DM1), the most common adult-onset form of ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 27 (July 7, 2020), pp. 15642-15649 (8 pages) The RNA polymerase (RNAP) trigger loop (TL) is a mobile ...