The innate immune system relies on intracellular sensor proteins to detect microbial motifs and danger signals. Upon recognition of such stimuli, nucleotide-binding oligomerisation domain-like ...

The complement system, a key component of innate immunity, exerts profound influence on the initiation, progression and destabilisation of atherosclerotic plaques. Activation may proceed via the ...

Distant metastasis and recurrence remain major obstacles limiting the long-term efficacy of immunotherapy for solid tumors, particularly in highly aggressive cancers, such as malignant melanoma.

A new review article highlights the powerful influence of long non-coding RNAs (lncRNAs) in regulating natural killer (NK) cells, revealing promising opportunities to enhance immune responses and ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways -- ways that have important implications for the development of ...

Scientists generally agree that eukaryotes, the domain of life whose cells contain nuclei and that includes almost all multicellular organisms, originated from a process involving the symbiotic union ...

Scientists discover how innate immunity envelops bacteria. The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites ...

Cabozantinib, a drug already used to treat patients with certain types of thyroid or kidney cancer, was able to eradicate invasive prostate cancers in mice by causing tumor cells to secrete factors ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

The immune system orchestrates a multi-step response to protect the body from infections and other diseases. Specifically, ...

We sometimes hear about the benefits of “boosting” our immune system, but what we really want to do is support our immune system on an ongoing basis. People often think of the immune system as ...