Please provide your email address to receive an email when new articles are posted on . The addition of modified FOLFIRINOX induction chemotherapy to standard care improved metastasis-free survival.

Neoadjuvant Therapy for Locally Advanced Rectal Cancer: Omission of Radiotherapy or Not? The following represents disclosure information provided by authors of this manuscript. All relationships are ...

A new treatment for locally advanced rectal cancer shows favourable results in that surgery can sometimes be avoided completely. It also reduces the risk of recurrence. The method has been confirmed ...

Please provide your email address to receive an email when new articles are posted on . Dostarlimab conferred clinical complete responses in all patients treated during a phase 2 trial.. Circulating ...

NG-350A received FDA fast track designation for mismatch repair-proficient locally advanced rectal cancer, addressing a significant unmet need in treatment options. Imfinzi combined with FLOT ...

Although rectal cancer is a life-threatening disease, it is highly curable in its early stages. Depending on the location and state of the cancer, surgery may be required. To avoid life-altering ...

Many patients with locally advanced rectal cancer treated with total neoadjuvant therapy in the OPRA trial achieved a complete or near-complete tumor response and were initially offered a ...

Sixteen patients with mismatch repair–deficient, locally advanced rectal cancer were enrolled in a pilot study in which 6 months of neoadjuvant anti–PD-1 therapy was to be followed by surgical ...