Eukaryotic cells have many specialized complexes and organelles that perform crucial functions. Mitochondria are well known organelles that are critical energy generators, often called the powerhouses ...

The tiny little powerhouses of our cells, the mitochondria, are unique among organelles because they carry their own tiny ...

The 100 or so organelles in sperm are swamped by hundreds of thousands of mitochondria embedded in each egg cell — each carrying the 37 genes in mitochondrial DNA. The contribution of only maternal ...

In most eukaryotes, the inheritance of mitochondrion and its DNA (mtDNA) is strictly maternal, despite the fact that a spermatozoon can inject up to 100 functional mitochondria into the oocyte during ...

Doubly uniparental inheritance (DUI) of mitochondrial DNA (mtDNA) represents a rare and intriguing deviation from the standard model of strictly maternal inheritance. In bivalves, DUI manifests as the ...

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its ...

Recombination occurs in human mitochondrial DNA, says a team from the Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, in a “proof of concept” paper in Science this week that ...

Maternal genetics extend far beyond mere aesthetics like eye color; they deeply influence our vitality, cognitive abilities, and resilience under pressure. The mitochondria, inherited from our mothers ...

Management of mitochondrial-related heart disease relies on multidisciplinary care and symptom control, as targeted gene-editing therapies are limited.

According to a recent AHA Scientific Statement, despite ongoing limitations, recent advances in genomic sequencing ...