Week 4 NFL odds, picks, predictions
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Check out an NFL Week 4 Monday Night Football same-game parlay that's an over bettor's dream, with five legs of attainable overs and +455 odds.
SportsLine's model enters Week 4 of the 2026 NFL season on a 54-43 run on top-rated picks dating back to 2024. One of its favorite picks at the best betting apps is the Giants (+2.5, 44.5) covering versus the Cardinals, which cashes almost 60% of the time. You can find the model's picks for every NFL Week 4 game here .