Protein translation is the ultimate paradigm for sequence-defined polymer synthesis. To introduce non-canonical monomers into the genetic code of living organisms, pairs of biomolecules known as ...
Before their involvement in translation, tRNAs undergo extensive processing and modification 1. Although most tRNA genes are intronless, a subset of pre-tRNAs contain an intron that forms base-pairing ...
Researchers from the University of Washington are developing new antibiotics targeting bacterial methionyl-tRNA synthetase (MetRS). This enzyme is responsible for charging tRNA (met) with methionine ...