C&EN1d
Top-Down Ion Mobility Mass Spectrometry Reveals a Disease Associated Conformational Ensemble of Alpha-1-antitrypsin
(61) A portion of this loop that would be protected from ECD if it was in ... All chromatography steps were performed using an AKTA Pure instrument (Cytiva) and sample purity was assessed by SDS-PAGE ...
Contract Pharma18h
Cytiva Expands Xcellerex X-Platform Portfolio
Cytiva is expanding its Xcellerex X-platform portfolio with the addition of 500L and 2,000L bioreactors.
eLife2d
Kinetic regulation of kinesin’s two motor domains coordinates its stepping along microtubules
This study provides compelling evidence that kinesin's stepping mechanism is governed by strain-induced conformational changes in its nucleotide-binding pockets. Using pre-steady state kinetics and ...
eLife5d
Structure-Guided Loop Grafting Improves Expression and Stability of Influenza Neuraminidase for Vaccine Development
The authors describe an approach to construct hybrid neuraminidase molecules that express epitopes (loops) of a specific neuraminidase ... with 10 μL of NA protein at 0.4 mg/mL, placed into the sample ...
The EMBO Journal2d
Structural insights into the selective recognition of RF-amide peptides by neuropeptide FF receptor 2
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neuropeptide FF Receptor 2 (NPFFR2), a ...