The San Francisco 49ers head to Southern California to take on the division-rival Los Angeles Rams on Sunday. They do so with ...

They’ll match their white jerseys with blue pants and socks, a nice contrast to the 49ers’ red-and-gold set that they’ll be ...

With college sports hungry for more marketing money (especially in the name, image, likeness era ), Cookies likely just ...

The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle reported soreness in his hamstring after Wednesday’s practice.

SANTA CLARA, Calif. (AP) — The San Francisco 49ers offense was dealt another blow with star receiver Deebo Samuel getting sidelined by a strained calf. Coach Kyle Shanahan said Monday that Samuel got ...

San Francisco 49ers rookie wide receiver Ricky Pearsall was shot Saturday afternoon in an attempted robbery in the Union Square area, San Francisco Mayor London Breed's office confirmed.

Sam Darnold passed for 268 yards and two touchdowns against his former team, including a 97-yard strike in the second quarter ...

Last season's AP Offensive Player of the Year missed the season opener, and now will have to sit out at least four more games ...

The 49ers and Vikings had two of the Top 5 most impressive wins during Week 1 of the NFL season, but only one can come away 2 ...

The All-Pro running back also missed last week's game with injuries to his calf and Achilles, which could keep him out an ...

49ers third-year running back Jordan Mason filled in admirably for McCaffrey in Week 1, rushing 28 times for 147 yards and a ...