The San Francisco 49ers don't play until Monday night this week, which makes Ricky Pearsall's injury situation all the more complicated for fantasy football players. He's a startable WR if healthy, but that's not a sure thing at this point. Pearsall is coming off a strong Week 15, when he had six catches for 96 yards.

Pearsall was ruled out Saturday by the 49ers after reinjuring a PCL strain late in in their 37-24 win over the Tennessee Titans. He did not travel to Indianapolis and will remain behind to rehab with the hope of getting him back for their Dec. 28 home game against the Chicago Bears.

USA Today's NFL experts make their picks for a Week 16 showdown between the Indianapolis Colts and San Francisco 49ers

According to SportsLine's Inside the Lines team, Indianapolis on Monday night has much more to lose in Week 16

San Francisco 49ers superstar running back Christian McCaffrey has a shot to making franchise history with a team legend in his crosshairs.

The 49ers placed linebacker Nick Martin on injured reserve after he continued to experience concussion symptoms ahead of Week 16.

NFL reporter Omar Ruiz gives the playoff implication of the San Francisco 49ers vs. the Indianapolis Colts matchup.

The San Francisco 49ers control their own destiny, but here is their nightmare playoff scenario with 3 weeks left in the regular season.