Cancer Research5d
$500,000 Purse Announced for TBXT Drugs
The Chordoma Foundation and some of its philanthropic partners announced that they will launch a competition offering $500,000 in prizes for the discovery of drugs targeting the protein TBXT, a ...
Cancer Research13d
Persistence and/or Senescence: Not So Lasting at Last?
1Medical Department of Hematology, Oncology and Tumor Immunology, Molekulares Krebsforschungszentrum – MKFZ, Campus Virchow Klinikum, Charité - Universitätsmedizin, Berlin, Germany.
Cancer Research6d
Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution
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Cancer Research5d
B7-H4 Inhibitor Effective for Some Triple-Negative Breast Cancers
Cambridge, MA–based Mersana Therapeutics announced today that its B7-H4–targeted antibody–drug conjugate emilatug ledadotin (XMT-1660) elicited a complete response in 23% (six of 26) of patients with ...
Cancer Research13d
MICAL2 Promotes Pancreatic Cancer Growth and Metastasis
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...
Cancer Research13d
Facts and hopes in neoadjuvant immunotherapy combinations in resectable non-small-cell lung cancer
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Cancer Research8d
Patient-Specific Hematologic Setpoints Inform Diagnosis and Prognosis
Main Findings: Complete blood count indices are patient-specific and stable over decades in healthy adults. Concept: These hematologic setpoints are deep physiological phenotypes associated with ...
Cancer Research7d
Tumor Suppressor Gene Zygosity Can Predict Therapeutic Response in Cancer
Main Findings: Assessing selection for biallelic loss of tumor suppressor genes (TSG) reveals TSG zygosity as an important feature of cancer etiology. Approach: An allele-specific analysis of somatic ...
Cancer Research13d
TOP1 Mutations and Cross-Resistance to Antibody-Drug Conjugates in Patients with Metastatic Breast Cancer
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...
Cancer Research9d
Acknowledgment to Reviewers
Clin Cancer Res (2025) 31 (1): 217–224. The Clinical Cancer Research editors wish to acknowledge with sincere appreciation the assistance of the following reviewers who have generously contributed ...
Cancer Research12d
Co-evolution of atypical BRAF and KRAS mutations in colorectal tumorigenesis
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license ...
Cancer Research9d
The Hallmarks of Predictive Oncology
4Princess Margaret Cancer Centre, University Health Network, Toronto, Canada. 12Medical Biophysics, University of Toronto, Toronto, Canada. 13Vector Institute for Artificial Intelligence, Toronto, ...