The San Francisco 49ers placed linebacker Nick Martin on the Injured Reserve. He’s been out since he suffered a concussion in ...

The Indianapolis Colts must emerge victorious against the San Francisco 49ers, or they'll add fuel to their doubters.

The San Francisco 49ers don't play until Monday night this week, which makes Ricky Pearsall's injury situation all the more ...

USA Today's NFL experts make their picks for a Week 16 showdown between the Indianapolis Colts and San Francisco 49ers ...

Pearsall was ruled out Saturday by the 49ers after reinjuring a PCL strain late in in their 37-24 win over the Tennessee ...

For the second time since they traded him, the San Francisco 49ers will face DeForest Buckner and the Indianapolis Colts. Or ...

The San Francisco 49ers will go into a vital Monday Night Football matchup vs. the Indianapolis Colts without two starters.

Colts coach Shane Steichen said starting DT DeForest Buckner will make his return Monday night vs the 49ers after missing 5 ...

San Francisco 49ers superstar running back Christian McCaffrey has a shot to making franchise history with a team legend in his crosshairs.

Colts coach Shane Steichen said DT DeForest Buckner will return from a neck injury and play vs the 49ers on Monday Night Football. The post 49ers Get Bad Defensive Line News Just Days Before Colts ...

The Indianapolis Colts announced some positive news ahead of the Week 16 matchup against the San Francisco 49ers.

Okuayinonu (ankle) does not carry an injury designation for Monday's game against Indianapolis. Okuayinonu will retake the field for the first time since suffering an ankle injury versus the Browns in ...