A new study combines genetic data and improved computational tools to look more closely at GWAS results for both adult-onset and childhood-onset asthma. The research identified many genetic variants ...

"So, when those variants overlap with open chromatin regions in cell types that are relevant to asthma pathogenesis like lung epithelial cells, we think that they are more likely to be causal to these ...

UChicago study combines genetic data with computational models to pinpoint likely genetic variations which cause asthma onset ...

Airway inflammation is a critical feature in the pathogenesis of asthma. Clinical investigation and testing are done to diagnose the disease and to identify the offending exposure. Testing ...

This syndrome is referred to as aspirin-induced asthma (AIA). The pathogenesis of AIA has implicated both the lipoxygenase (LO) and the cyclooxygenase (COX) pathways. By inhibiting the COX pathway ...

Deciphering the gut biome's, including helminths', influence on human trained immunity will unlock novel immunotherapies harnessing the immune reprogramming potential of their secreted factors and ...