Airway inflammation is a critical feature in the pathogenesis of asthma. Clinical investigation and testing are done to diagnose the disease and to identify the offending exposure. Testing ...

A new study combines genetic data and improved computational tools to look more closely at GWAS results for both adult-onset and childhood-onset asthma. The research identified many genetic variants ...

"So, when those variants overlap with open chromatin regions in cell types that are relevant to asthma pathogenesis like lung epithelial cells, we think that they are more likely to be causal to these ...

Other research interests include the pathophysiology of asthma and allergic diseases as well as primary immune deficiencies and autoimmunity.