Researchers from Hallym University and Eulji University in the Republic of Korea report that activating cannabinoid receptor 1 (CB1) boosted several key wound-healing processes in human skin cells and ...
Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...
Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2418624122 Scientists have uncovered new details about cellular filaments that play a critical role in wound healing, ...
A NOVEL autoimmune meningoencephalomyelitis associated with autoantibodies targeting the astrocytic intermediate filament protein vimentin has been identified in a recent case series. This discovery ...
Vimentin, a type III intermediate filament (IF) protein, forms filaments which are an integral part of the cell cytoskeleton. We study a mutant vimentin which cannot form filaments. We show that it ...
Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. The authors investigate the mechanism behind the widely ...
This valuable study provides new insight into the disassembly of vimentin filaments and the dependence of this mechanism on net charge, albeit with incomplete evidence. In particular, the experimental ...
A recent iScience journal study reports that cell-surface vimentin functions as a co-receptor for the entry of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into host cells to ...
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