The Chordoma Foundation and some of its philanthropic partners announced that they will launch a competition offering $500,000 in prizes for the discovery of drugs targeting the protein TBXT, a ...
1Medical Department of Hematology, Oncology and Tumor Immunology, Molekulares Krebsforschungszentrum – MKFZ, Campus Virchow Klinikum, Charité - Universitätsmedizin, Berlin, Germany.
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Cambridge, MA–based Mersana Therapeutics announced today that its B7-H4–targeted antibody–drug conjugate emilatug ledadotin (XMT-1660) elicited a complete response in 23% (six of 26) of patients with ...
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Main Findings: Complete blood count indices are patient-specific and stable over decades in healthy adults. Concept: These hematologic setpoints are deep physiological phenotypes associated with ...
Main Findings: Assessing selection for biallelic loss of tumor suppressor genes (TSG) reveals TSG zygosity as an important feature of cancer etiology. Approach: An allele-specific analysis of somatic ...
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...
Clin Cancer Res (2025) 31 (1): 217–224. The Clinical Cancer Research editors wish to acknowledge with sincere appreciation the assistance of the following reviewers who have generously contributed ...
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license ...
Glutathione S-Transferase P (GSTP) known as a Phase II detoxification enzyme has more recently been identified as a modulator of MAP kinase-related cell-signaling pathways. It is known to be ...
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