BACKGROUND Erythromycin has been reported to have an inhibitory effect on chronic inflammatory airway disease and chronic infiltration of neutrophils into the airway. Bleomycin (BLM) often induces ...

1 David Read Laboratory, Department of Medicine, University of Sydney, NSW 2006, Australia 2 Department of Respiratory Medicine, Westmead Hospital, Westmead, NSW 2145, Australia Correspondence to: Dr ...

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Background: Oxidative stress is thought to have a major role in the pathogenesis of airway obstruction. A study was undertaken to determine whether subjects with low levels of antioxidants (serum ...

Introduction Despite the introduction of dedicated asthma services and targeted therapies, asthma exacerbations remain a common cause of hospital admission with significant utilisation of health care ...

8 Department of Environmental Medicine and Public Health, Section of Occupational Medicine, University of Padova, Italy 9 Departments of Medicine, Oncology and Radiology, Section of Respiratory ...

Introduction and Objectives Cardiac arrhythmias are regularly found in patients with COPD, with higher frequencies reported during exacerbations. We wished to examine the impact of tachycardia and new ...

1 Department of Geriatric Medicine, Royal United Hospital Bath NHS Trust, Bath, UK 2 Department of Respiratory Medicine, Glenfield Hospital, Leicester, UK 3 Department of Respiratory Medicine, ...

aDepartment of Pulmonary and Mediastinal Pathology, Armed Forces Institute of Pathology, 6825 N W 16th Street, Bld 54, Rm M003B, Washington, DC 20306-6000, USA, bDepartment of Thoracic Radiology, ...

Background Tissue factor pathway inhibitor (TFPI) attenuates intravascular coagulation, a function limited by its proteolysis. Airway inflammation in COPD is associated with protease activity and ...

Objective Anaesthesiology guidelines suggest that opioids worsen obstructive sleep apnoea (OSA) despite no randomised controlled trial evidence. We therefore conducted a randomised controlled trial to ...