In molecular biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the …

Jun 23, 2020 · By phosphorylating widely diverse substrates, ERK proteins govern a variety of evolutionarily conserved cellular processes in metazoans, the dysregulation of which contributes to …

Extracellular signal-regulated kinase (ERK) is a member of the mitogen-activated protein kinase family of signaling molecules. ERK is predominantly found in two forms, ERK1 (p44) and ERK2 (p42), …

Extracellular signal-regulated kinases (ERKs) are widely used intracellular serine/threonine-protein kinase signaling molecule that regulates a variety of cellular functions, including mitosis, meiosis and …

Dec 24, 2023 · The ERK pathway is a key cell signaling system activated by physiological factors or oncogenic mutations, influencing different cell outcomes. The protein kinases ERK1 and ERK2 …

5 days ago · The MAPK/Erk signaling cascade is activated by a wide variety of receptors involved in growth and differentiation including receptor tyrosine kinases (RTKs), integrins, and ion channels.

The ERK pathway plays an important role of integrating external signals from the presence of mitogens such as epidermal growth factor (EGF) into signaling events promoting cell growth and proliferation …

Extracellular signal-regulated kinase (ERK) has long been studied as a key driver of both essential cellular processes and disease. A persistent question has been how this single pathway is able to …

Apr 9, 2018 · Cell signaling is the process by which extracellular information is transmitted into the cell to perform useful biological functions. The ERK (extracellular-signal-regulated kinase) signaling controls …

Read our article on The ERK Signal Transduction Pathway and its role in growth factor signaling and cancer.