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👇Patellar subluxation occurs when the kneecap (patella) partially slips out of its normal groove at the end of the thighbone (femur), usually toward the outer side of the knee. It is different from a complete patellar dislocation, in which the kneecap completely leaves the groove. Subluxation can happen after a sudden twisting movement, sports injury, awkward landing, or direct blow to the knee. Some people are more prone to it because of naturally loose ligaments, abnormal leg alignment, a sha
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Administering low-dose intravenous ketamine transforms multimodal general anesthesia by targeting central pain pathways before surgical stimulation begins. Ketamine functions as a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, dampening dorsal horn wind-up and preventing acute central sensitization (Peltoniemi et al., 2016). When combined synergistically with gamma-aminobutyric acid (GABA) receptor agonists like propofol, it produces reliable hypnotic depth and somatic analgesia
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